Should Seed Be an Alternative Source of Camptothecin From Nothapodytes nimmoniana and Chonemorpha fragrance?
نویسندگان
چکیده
منابع مشابه
Direct analysis of camptothecin from Nothapodytes nimmoniana by desorption electrospray ionization mass spectrometry (DESI-MS).
Desorption electrospray ionization was employed for fast and direct ambient detection of the anti-tumor drug, camptothecin, and its derivative, 9-methoxycamptothecin in Nothapodytes nimmoniana. Different parts of the plant such as leaves, stems and bark were examined. The ion intensities suggest that the concentration in bark is higher than that in the leaves and stems. The method does not requ...
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Camptothecin, topoisomerase I-DNA inhibitor, has been evaluated in methanolic extract of various parts of Nothapodytes nimmoniana (J. Graham) Mabberly (Family Icacinaceae) collected in the month of February from different regions (Mahabaleshwar and Patan regions of Maharashtra state and Sirsi region of Karnataka state) of Western Ghats, India, using high performance liquid chromatography. Quant...
متن کاملCompound Specific Extraction of Camptothecin from Nothapodytes nimmoniana and Piperine from Piper nigrum Using Accelerated Solvent Extractor
Effects of varying temperatures with constant pressure of solvent on extraction efficiency of two chemically different alkaloids were studied. Camptothecin (CPT) from stem of Nothapodytes nimmoniana (Grah.) Mabb. and piperine from the fruits of Piper nigrum L. were extracted using Accelerated Solvent Extractor (ASE). Three cycles of extraction for a particular sample cell at a given temperature...
متن کاملPharmacognostical and Phytochemical Analysis of Nothapodytes Nimmoniana Stem
Medicinal plants play a vital role for the development of new drugs. Preliminary pharmacognostical screening was studied in Nothapodytes nimmoniana stem to establish authenticity and possible to help and distinguish the drug from other species. Nothapodytes nimmoniana contains camptothecin which is used in the treatment of colon, stomach, breast and bladder cancers. Different physicochemical pa...
متن کاملSeasonal Discrepancy in Phenolic Content and Antioxidant Properties from Bark of Nothapodytes Nimmoniana (grah.) Mabb
Seasonal discrepancy in the antioxidant potential from bark of Nothapodytes nimmoniana was evaluated using two different methods (DPPH and FRAP) and were related to total phenolic content as well as flavonoid content. Higher yield of phenolic and flavonoid were observed during summer (May) similarly, the antioxidant activities (DPPH & FRAP) also were high. The antioxidant activities were strong...
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ژورنال
عنوان ژورنال: Pharmacognosy Journal
سال: 2016
ISSN: 0975-3575
DOI: 10.5530/pj.2016.6.11